PostEaseModeration load increases faster than most accounts expect
A sudden spike in comments, including a higher share of spam and bad-faith replies than usual, can overwhelm a routine moderation approach quickly. Having a moderation policy already in place before this happens means the response is a matter of applying existing rules, not making them up under pressure.
A wave of new followers is a real, if brief, opportunity
Many of the new followers a viral moment brings will not stay engaged unless something gives them a reason to. A follow-up post in the days right after, one that builds on the viral moment or introduces the rest of the account's content, converts more of that spike into a lasting audience.
Do not force a repeat of the same format immediately
The instinct to immediately try to replicate exactly what went viral often produces a weaker, more obviously derivative follow-up. A genuine follow-up that builds on the underlying interest, rather than a forced repeat of the exact format, tends to perform better and feels less opportunistic to an audience that is already watching closely.